Another recent study found that greater longest baseline left ventricular activation time and smaller scar volume on electrocardiogram (ECG) combined with wavefront fusion on the paced ECG, anticipate higher probability of reverse remodeling. QRS morphology seems to be able to identify patients who benefit from CRT, as shown by a recent study, which documented that no clinical benefit was observed in patients with right bundle‐branch block (RBBB) or intraventricular conduction delay (IVCD). However, the performance of QRS duration to predict CRT response in heart failure patients with widened QRS duration is unimpressive, because the results of these studies have been conflicting. QRS duration has been used to select patients for CRT since early 2000s, while many studies have focused on the potential value of QRS duration in predicting CRT response. Numerous echocardiographic parameters of ventricular dyssynchrony have been explored, but none has emerged as a predictor of response to CRT in a multicenter study. Therefore, determination of predictors of response to CRT is of important clinical significance. However, even using the well‐recognized criteria to select patients for CRT, the rate of CRT response is just about 60–70%, which varies when using different response criteria. CRT has been confirmed to improve left ventricular systolic function, reverse left ventricular remodeling, improve clinical symptoms as well as reduce mortality. INTRODUCTION During the past 10 years, the benefits of cardiac resynchronization therapy (CRT) for patients with reduced left ventricular systolic function and prolonged QRS have been well established. Pan, Wenzhi Su, Yangang Zhu, Wenqin Shu, Xianhong Ge, Junbo Notched QRS Complex in Lateral Leads as a Novel Predictor of Response to Cardiac Resynchronization Therapy Notched QRS Complex in Lateral Leads as a Novel Predictor of Response to Cardiac.
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